Friday, May 25, 2012

South Sudan's history emerges - from a tent

JUBA (Reuters) - South Sudan's independence last July was forged through years of hard-fought rebellion in the bush, so it seems fitting that the world's newest nation still keeps much of its history in a tent.

The weather-beaten brown tent in a roadside government compound in the capital Juba goes unnoticed by most passing drivers and pedestrians. Musty papers, files, books and photos, some honeycombed with termites, litter its stifling interior.

But this unassuming collection of paper, which would probably not qualify for a jumble sale in the West, holds part of the historical memory of Africa's most recent state, straddling the White Nile and its vast Sudd swamp.

Piled higgledy-piggledy on the grimy concrete floor and on old tables, or bursting out of sacks, the documents in the tent are a treasure trove of records dating back to the early 1900s, when Sudan and its remote South was under Anglo-Egyptian rule.

The collection of civil service files and official reports tracks the southern territory's history through unified Sudan's independence in 1956 and the years that followed which saw back-to- back civil wars fought by African rebels - now South Sudan's rulers - against governments in the largely Muslim North.

The papers, languishing under canvass for several years since a 2005 North-South peace deal, have survived fire, war and the elements. They are the core of what will be South Sudan's National Archives - that is, once they are rescued and housed in a new building promised as an independence gift by Norway.

"There is no nation without history," said Youssef Fulgensio Onyalla, 48, senior inspector for Museums and Monuments at South Sudan's Ministry of Culture and Heritage which is racing against time - and the termites - to recover and preserve the archives.

"Thank God, we are working to bring the archives alive," said Onyalla, who studied archeology at the Lebanese-American University in Beirut before returning to his home nation.

The National Archives form part of an ambitious project, still in its infancy, to endow the emerging nation with a panoply of cultural heritage institutions, including a National Museum, National Library, National Theatre and Cultural Centre.

These cultural aspirations may seem lofty, even unreal, in a newborn African nation of more than 8 million people that despite its oil resources is one of the least developed on earth, and where more than 70 percent of the population are illiterate.

But South Sudanese officials say forging a national identity out of a complex patchwork of more than 70 ethnic groups, some of them traditional historical foes, is as important a part of nation-building as constructing roads, schools and clinics.

"You can't strengthen a state without strengthening the minds and hearts of the people," Undersecretary for Culture Jok Madut Jok, one of the country's most respected intellectuals, told Reuters.

CRUCIBLE OF LIBERATION WAR

Forging this national consciousness is no small challenge in a nation where ethnic enmities over cattle, water and grazing rights, exacerbated through the centuries by slave-raiding and in recent decades by the brutal civil war, still trigger outbursts of bloodshed.

"It's something that will take a generation ... countries are not born, they are made," said Jok, who has a PhD in Anthropology from the University of California, Los Angeles (UCLA).

The need for a sense of nationhood has become all the more urgent as South Sudan's guerrilla commander-turned-statesman President Salva Kiir urges its citizens to brace for continuing hardships in the face of persisting military and economic confrontation with northern neighbor Sudan.

Patriotism runs high among ordinary people in Juba and South Sudan's independence from Sudan last year, the result of the liberation struggle fought since 1963 that killed more than 2 million people, is a powerful agglutinant of national identity.

"The challenge is to transition to being a member of a nation state, rather than a citizen of an ethnic group. Most people are loyal to their ethnic ties," Jok said.

Juba abounds with Kenyans, Ugandans and citizens from other neighboring states but most locals, when asked where they come from, proudly respond "I am South Sudanese". Many would struggle to sing the new national anthem, whose words are in English, however.

References to the spilled blood of the nation's "war martyrs" are a staple of major speeches and the bearded image of independence hero Dr. John Garang, a Dinka warrior and U.S.-trained founder of the ruling Sudan People's Liberation Movement (SPLM), peers down from the walls of most government offices.

His face also adorns the new South Sudanese banknotes.

"What binds South Sudan together is that they gained independence, but there was something here before, and there will be something after," said Elke Selter, a culture program specialist working for UNESCO South Sudan.

Salah Khaled, the head of South Sudan's UNESCO office, believes that tapping into common cultural traditions, for example funerals and marriages, and oral histories is one way of seeking common traits and customs among the country's diverse peoples.

"We need to find the common denominator between them," Khaled said.

As a way of creating a collective identity, Jok has devised the idea of a travelling cultural exhibit of artifacts like cooking and farm utensils, weapons and musical instruments.

This will traverse the nation, picking up new items and at the same time showcasing South Sudan's great variety of ethnic groups - the Dinka, Merle, Nuer, Bari and others.

"It's the embryo of the national museum ... You put them all together and say ?this is what they are used for'... People will see the commonality, but also the diversity," Jok said.

MINUTIAE OF COLONIAL BUREAUCRACY

In the strength-sapping heat of the archives tent, even a cursory inspection shows the wealth of historical record it contains - a gold mine of potential knowledge for historians, researchers, students and, one day, tourists.

In English and Arabic, set down in neat but florid handwriting or typewritten, the files reveal the minutiae of Sudan's colonial and post-1956 independence bureaucracy in the South, including budgets, personnel and official reports on topics from maps and minerals to land and tribal disputes.

Colonial era correspondence on yellowed paper from 1935 requests a meeting to discuss "matters affecting the Madi fishing in Sudan waters", an example of tribal issues that local district commissioners were often called upon to deal with.

A large amount of documents in the tent refer to the 1970s, a period when South Sudan was governed by a High Executive Council during the rule in Khartoum of President Jaafar Nimeiri.

A dusty painted portrait of Nimeiri in military uniform is propped up against a table in the middle of the tent.

Faded official black and white photographs strewn about show visiting royalty, including the late Ethiopian Emperor Haile Selassie and Britain's Princess Anne.

In one corner stand grime-covered shields of the Nuer tribe, native spears and a basket of the Bari people.

South Sudan has approached Sudan requesting the repatriation of archives and documents pertaining to its history.

But some are sensitive, for example security files on the Sudanese army's operations in the South during the long years of civil war, or maps or treatises on oil or mineral deposits, which could become vital evidence in the South's ongoing disputes with the North over where the border is and who owns the oil.

Rummaging among the papers, journalists find what appears to be a 1957 map that covers the now disputed border area in a file riddled with termite holes and encrusted with the burrowing insects' earthy secretions. Onyalla carries it away for study.

His team has begun the task of moving files from the tent to more hospitable premises in Juba, cataloguing and storing them.

One third of the archives have already been transferred in an initiative backed by Norway and the United States. The U.S. embassy provided funds to supply protective cardboard archive files and electronic scanners to copy documents.

But there is an urgent need for more money.

UNESCO's South Sudan office, which is also helping the new country tackle its enormous educational deficit, is drawing up a cultural strategy that can be presented to donors.

But it is a tough sell at a time when aid budgets are being pared back and South Sudan's government needs to pay for infrastructure, health, education and defense.

"In a country where everything is a priority now, how can arts and culture compete with the construction of a school or a clinic?" South Sudan's cultural champion Jok says ruefully.

(Additional reporting by Hereward Holland; Editing by Sonya Hepinstall)

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A-Rod powers Yankees with pair of homers

By HOWIE RUMBERG

AP Sports Writer

Associated Press Sports

updated 10:26 p.m. ET May 23, 2012

NEW YORK (AP) - On Tuesday night, after another mediocre game at the plate, Alex Rodriguez insisted he was ready to go on a tear.

He knew what he was talking about.

A-Rod gave Will Smith a rude welcome to the major leagues Wednesday night, hitting two homers off the rookie to back another strong start for Andy Pettitte and lead the New York Yankees over the Kansas City Royals 8-3.

"I said it with conviction not because it was going to sound good here in my locker but because I felt it," Rodriguez said. "It's good to back that up."

Rodriguez snapped a 52 at-bat homerless drought and drove in three runs for New York. Curtis Granderson also connected off Smith and the Yankees scored three times in the fifth with help from some inept relief pitching.

Derek Jeter had three hits to tie Paul Waner for 15th with 3,152. Before Jeter singled in the eighth, Waner had been the only player who reached a bigger hits milestone than Jeter in a Yankees uniform. "Big Poison" got just one hit with New York, his final one in a career spent mostly in Pittsburgh.

New York scored as many as three runs in the first inning for the first time in 31 games since April 19 and finished a 3-3 homestand. The Yankees start a 10-game trip at Oakland on Friday following their first consecutive wins since taking three in a row from May 10-12.

Pettitte (2-1) followed eight innings of four-hit ball against Cincinnati with seven-plus crafty innings in his third start since coming out of retirement. He gave Smith a lesson in mixing pitches and working out of difficult situations.

"I feel like I'm moving the ball around the zone and that makes it difficult to hit," Pettitte said.

In the third inning, first baseman Mark Teixeira started a double play with a diving stop. Pettitte got out of a bases loaded jam in the fourth with a strikeout - one of his eight Ks - giving a slight fist pump walking off the mound.

"He's as good as I've ever seen over there," Pettitte said about Teixeira.

Pettitte gave up seven hits, including homers to Billy Butler and Mitch Maier. The 39-year-old left-hander has not lost to Kansas City since 1999. In 24 games against the Royals, he is 14-3.

"I faced him before he retired and now after he came back, and I actually see things different that he's doing," Butler said. "He's throwing more off-speed stuff, more curveballs and changeups. Before it was 90 to 94 with hard cut in on you. You knew he was throwing it and he knew you knew he was throwing it, and it was going to beat you. But he's crafted his game and his last two starts have been great."

Smith (0-1), a 22-year old called up from Triple-A Omaha on Tuesday - not the actor with a movie coming out this weekend - started off with an out for the scrapbook: He got Jeter to hit a grounder to shortstop. But it was rocky the rest of the first for the lefty who was two months shy of 6 when Pettitte made his debut in 1995.

"I was nervous a little bit, facing a future Hall of Famer to start your career, in Derek Jeter," Smith said. "That was cool at the same time, but you still got to go out there and make your pitches and get people out."

Granderson homered to deep right on a 1-2 pitch. TV showed Smith's mom in the stands shaking her head: welcome to the big leagues, son. After a walk to Teixeira, A-Rod crushed a ball into the left field stands for a 3-0 lead.

By the time Nick Swisher hit a pop up with two outs, Smith's mom couldn't watch: she had covered her face with her hands. It was an out, mom.

When Rodriguez homered in the third to center field, mom sat stunned with her hands behind her head.

"She was nervous. She's been like that since I was in high school," Smith said. "She and my dad ... my dad used to pace around the stadium. They always get nervous and always will be."

Rodriguez had just one RBI since he last homered and drove in three runs on May 6 at Kansas City, 15 games ago. It was Rodriguez's 60th multihomer game.

Smith was lifted after giving up a one-out single in the fourth. He yielded five runs and six hits in 3 1-3 innings. Luis Mendoza, the pitcher originally slated to start Wednesday night, relieved.

Rodriguez came up in the fifth with the bases loaded and grounded into a fielder's choice. Jeter, who bunted for a hit, was forced out at home.

The Yankees came in 8 for 41 (.195) with the bases loaded but they didn't need a hit in that situation in the fifth to score their runs. The Yankees walked three times and were twice hit by pitches in the inning. Robinson Cano had an RBI fielder's choice - a nice diving stop by shortstop Alcides Escobar - and Andruw Jones and Teixeira, back in the 3-hole after two games batting seventh, walked to force in runs.

"It's a club that a lot of times works the count really well and is going to have its share of walks," Yankees manager Joe Girardi said.

Eric Hosmer went 3 for 4 with an RBI to raise his average to .191 for the Royals.

NOTES: The Royals dropped to 4-3 in the deciding game of series this season. ... New York went 1 for 6 with runners in scoring position, leaving the Yankees 9 for 85 (.106) in their last nine games.

? 2012 The Associated Press. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.


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Cole Hamels pitched eight scoreless innings, finishing up by retiring Bryce Harper on a grounder as the Philadelphia Phillies snapped a season-long four-game losing streak Wednesday night with a 3-1 victory over the Washington Nationals.

A-Rod powers Yankees with pair of homers

NEW YORK (AP) - Alex Rodriguez gave Will Smith a rude welcome to the major leagues Wednesday night, hitting two homers off the rookie to back another strong start for Andy Pettitte and lead the New York Yankees over the Kansas City Royals 8-3.

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May 24: CD Release Party; Business Networking - Agoura Hills Patch

1. The Forecast: Sunny, 78

It will be sunny with a high near 78, according to the National Weather Service. Tonight skies will be cloudy and there's a chance of drizzle with a low around 54.

2. CV Bing Networking Lunch

The Conejo Valley Business Independent Networking Group meets every Thursday at 12 p.m. at Vitello's, except the third Thursday is 8:45 a.m. at Mimi's Cafe. For more information, call 818-991-2235 or click here.

3. Maddy's Discount

Readers who mention Patch at Maddy?s checkout receive 10% discount.

4. Amanda Ply CD Release Party at the Canyon Club

The local artist celebrates the release of her latest work. The show starts at 7 p.m. and tickets are $10.

5. Get Your Tickets for the T.H.E. Event

Hollywood heads to the suburbs for the first annual T.H.E. Event benefiting the Las Virgenes Unified School District.This is a new initiative focused on bringing together a diverse group of community influencers for one night in the name of the local public schools. All of the proceeds from T.H.E. Event will go to T.H.E. Foundation, which is dedicated to saving the jobs of teachers and counselors in the Las Virgenes Unified School District that are at risk due to continued budget cuts. For more information, go to http://www.theeventparty.org/

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Piers Morgan "showed journalist how to hack phone"

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Thursday, May 24, 2012

The Real Estate Scene in British Columbia, Canada | Real Estate ...

Real Estate Investing involves buying, selling, managing and renting real estate for financial gain. Many rich Canadians are investing in real estate in Canada to maximize their capital gains and for financial security.
To invest in canada, especially in British Columbia, you need to do some extensive research to know the current and the future opportunities for real estate investment. As a prospective investor, you should analyze the British Columbia Real Estate market closely to see which cities have the potential for growth in the coming decade.
The British Columbia property market, though reviving from a bit of a low period, is currently booming and it is the right time to invest in positive cash-flow properties here. Customer confidence is on the rise and the mortgage interest rates are quite low. This has created a positive environment for investors and perked up residential property sales this year.
The city of Vancouver has attracted the most interest of the British Columbia land and buildings market. Not only real property investors but also home buyers, young and old alike are rushing in for their dream investment. There is certainly no shortage of opportunities in the present real estate market condition. Currently, it is expected that the price of residential property in the British Columbia area could rise by 8% and more than double of that in Vancouver. In Downtown Vancouver, the prices of condos will be pushed from CAD $500 per square feet to about $1000 per square feet, making the city the seventh most expensive place in the world to stay in. The city of Victoria is also experiencing record sales in this quarter.
Surrey is another city growing fast in terms of the British Columbia landed property market. With major infrastructure and transportation projects coming up, the city will experience explosive population increase and this is definitely a good indication for property growth. The other towns in the British Columbia region which have a lot of potential in the landed property investment scene are Abbotsford, Kamloops, Kelowna, Dawson Creek, Oliver, Fraser Valley, Maple Ridge and Pitt Meadows.
However, it is to be remembered that the free hold market is not an organised one; hence, the investor is expected to put in a lot of personal effort and time. The investor has to first locate the properties in which to invest, and then investigate and properly verify the status of the property, prior to purchase. He has to bargain hard and negotiate a sales price with the seller and finally, draw up a sales contract with the assistance of a land holdings attorney.
Real Estate Investing Forums can be a good way to get your land holdings queries answered and stay abreast of current market trends in Real Estate, Canada, like the right place to invest in, the correct prices to expect and most importantly, the right time to sell. Whether you are a new investor or a seasoned one, participating in real property investing forums offers opportunities to connect with like minded people from all around the world and freely share strategies and experiences.
Complete solutions on real estate investment Canada or else discuss in real estate investment forum with experts.

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Skepticism over EU breakthrough hits markets

LONDON (AP) ? Skepticism over the ability of European Union leaders to cobble together a plan to kick-start the region's faltering economy and deal with its crippling debt crisis hit stock markets hard Wednesday and sent the euro skidding down to near 21-month lows against the dollar.

Leaders of the 27 EU countries are to meet in Brussels later for a summit that will focus on Europe's economic woes and Greece's political crisis. An election in Greece on June 17 is widely considered to be a referendum on the country's membership of the euro and that's caused big jitters in the markets over the past couple of weeks.

"The market remains focused on the uncertain European situation, with today's European leaders meeting doing little to ease market worries," said Nick Bennenbroek, an analyst at Wells Fargo Bank.

In the early part of the week, there had been some hope that the summit might make progress towards shoring up Europe's defenses against financial turmoil. Any enthusiasm appears to have vanished with Germany's continued refusal to back the idea of jointly-issued eurobonds. Proponents of eurobonds say they could help mitigate the crisis by spreading debt risk across the single currency zone.

"Hopes for today's EU summit have been well and truly chucked out of the window, as the Germans once again state their firm opposition to eurozone bonds as a means of solving the crisis," said Chris Beauchamp, market analyst at IG Index.

In Europe, Britain's FTSE 100 was 1.9 percent lower at 5,304, while Germany's DAX lost 1.7 percent to 6,326. The CAC-40 in France was 2.1 percent lower at 3,019.

The euro was also under pressure, trading 0.5 percent lower at $1.2588 ? its lowest level since August 2010.

Wall Street opened lower too, with the Dow Jones industrial average down 0.7 percent at 12,416 and the broader S&P 500 index 0.6 percent lower at 1,308.

Europe's battle to contain its debt crisis, now well into its third year, is likely to remain the focus of attention all the way up to and beyond the Greek election.

The main concern is that political parties that are against the terms of the country's bailout package winning will win the election. If Europe then cuts off its funding to Greece, the country may face a messy exit from the euro, raising concerns among investors that other countries might follow. Some analysts say a Greek exit would herald the beginning of the end of the euro and could slam the global economy.

Another big worry for investors is a slowdown in Chinese growth, compounded by a reluctance of Chinese companies to borrow because of uncertainty about the economy.

Those concerns dented sentiment earlier in Asia. Japan's Nikkei 225 index tumbled 2 percent to close at 8,556.60, while Hong Kong's Hang Seng fell 1.3 percent to 18,786.19 and South Korea's Kospi lost 1.1 percent at 1,808.62.

Oil prices were near seven-month lows as they tracked equities and amid hopes that the standoff between Iran and western powers over the country's nuclear program may be ending. Iran has agreed to allow the U.N. nuclear agency to restart an investigation into its nuclear program. Benchmark oil for July delivery down 50 cents at $91.35 a barrel in electronic trading on the New York Mercantile Exchange.

____

Pamela Sampson in Bangkok contributed to this report.

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Enhance online Ranking of your website with Search marketing

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Teen Dating: First Relationships Can Turn Abusive - Poway, CA Patch

Love and trust should not equal fear. As we jump into the start of the summer, the beautiful purple flowers stand proud, and the color purple is known nationally as a symbol of courage for domestic violence survivors. We are brought together this Memorial Day weekend in remembering and honoring sacrifices and freedoms.

Sadly, in our communities, teen dating violence and unhealthy relationships among teens are becoming more prevalent than ever. According to SafeAtSchools.org, there have been at least 20 teen dating abuse murders in California in the last three years. As teens seek love and attention from their peers and dating relationships develop, so does teen-dating violence.

Both boys and girls can become victims, but the abuse usually happens in different ways, and boys tend to injure girls more severely. Teens are especially vulnerable?some may not understand the power and control they can wield, and others may thrive on the attention, even if it is ugly.

Operation For HOPE Foundation spoke with a male teen survivor about a past relationship that was filled with verbal and emotional abuse.

My partner was emotionally abusive. It hurt more than I believe any physical violence could, as it always led to who could get the most hurtful word in to hurt the other. We wouldn?t text but we would call as to say the words directly to each other. Now, looking back, this relationship was toxic. I did bad things, too, in our relationship as the pain I was feeling really hurt. She really wanted to cause me great pain.

Now, in the light, we both had such terrible tempers and I am thankful I am not in this relationship and that it has stopped. It was like pouring gasoline on a fire. One minute, it was all about love and the next, everything was about hate. We were so close to one another and not able to make it stop. I never told anyone as I wanted to keep it private and I wasn?t willing to share. I always acted like everything was OK.

But in the end, this caused me to be depressed and I attempted to take my own life. Today, after receiving professional help and with the support and love of my friends, family and especially my mom, I now talk things out and I don?t hold them in. I am still not the same, as this has caused great impacts on my life. I am slowly regaining myself and with the love of my family and friends, I am able to talk through my emotions and really appreciate even more my many good relationships with others.

There are ways that we as a community can help educate teens about unhealthy relationships. It starts in our homes by setting an example for our teens to follow, and should continue in our schools, organizations and larger communities. It?s important to speak to our children about healthy relationships, mutual respect and trust. It?s also important to create awareness about dating violence and to learn if they have witnessed any of their friends or fellow students become victims of dating violence.

Our children should feel safe and connected to school. Let?s make our schools healthier and safer for all students by having prevention efforts in place and resources available that they can turn to. We can all help by reviewing our school policies on dating violence and making sure our children are familiar with school resources including teachers, counselors, social workers and nurses.

Remember love and trust should not equal fear. Each of us has a role and by stopping a problem before it starts?we all deserve to stand proud!

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Wednesday, May 23, 2012

Early-life risk factors for non-Hodgkin lymphoma

Early-life risk factors for non-Hodgkin lymphoma [ Back to EurekAlert! ] Public release date: 22-May-2012
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Contact: Zachary Rathner
Zachary.Rathner@oup.com
301-841-1286
Journal of the National Cancer Institute

Factors influencing early life non-Hodgkin lymphoma (NHL) incidence include family characteristics, high fetal growth, older maternal age, low birth order, and male gender, according to a study published May 22 in the Journal of the National Cancer Institute.

Over the last 50 years, NHL incidence increased substantially, although the overall incidence started to stabilize in the 1990s, at least among adults. But incidence has continued to climb in children, adolescents, and young adults. Perinatal factors have been thought to increase NHL risk, but previous studies of those factors were limited due to small sample sizes, wide variability in adjustment for confounding, and possible selection bias such as socioeconomic circumstances.

In order to determine the cause of NHL incidence in children, adolescents, and young adults, Casey Crump, M.D., Ph.D., of the Department of Medicine at Stanford University and colleagues, conducted a national cohort study of more than 3.5 million people born in Sweden between 1973-2008 who were followed for NHL incidence through 2009. Information on perinatal and family characteristics and NHL diagnoses were attained through linkage of national birth and cancer registries, and Cox proportional hazard models were used to assess association of those characteristics with the risk of NHL.

The researchers found that genetics and in utero conditions contributed to the incidence of NHL in adolescents. The strongest link was a family history of NHL in either a sibling or parent. A high fetal growth rate, older maternal age, and low birth order also played a key role in incidence rates. Male gender was linked with NHL incidence in children younger than age 15, but not with later onset of NHL. "These findings suggest several heterogeneous mechanisms including possible growth factor pathways in utero, immunologic effects of delayed infectious exposures, as well as other unmeasured environmental and genetic factors," the authors write. "Further elucidation of these risk factors may facilitate the identification of high-risk individuals at young ages and potentially enable earlier detection and treatment."

In an accompanying editorial, William F. Anderson, M.D., M.P.H., and Benjamin Emmanuel, MPH, of the National Cancer Institute at the Division of Cancer Epidemiology and Genetics, write that this is a "well-performed national cohort study," but point out certain limitations, including: the unavailability of host and environmental risk factors such as radiation and environmental contaminants. They also point out the small number of case patients. However, they conclude that the study's, "large-scale and population-based design minimized selection bias and maximized generalizable conclusions for associations between NHL in early life and family history, high fetal growth weight, older maternal age, low birth order, and male sex."

###

Contact Info:

Article: Casey Crump. kccrump@stanford.edu

Editorial: William F. Anderson, wanderso@mail.nih.gov


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AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


Early-life risk factors for non-Hodgkin lymphoma [ Back to EurekAlert! ] Public release date: 22-May-2012
[ | E-mail | Share Share ]

Contact: Zachary Rathner
Zachary.Rathner@oup.com
301-841-1286
Journal of the National Cancer Institute

Factors influencing early life non-Hodgkin lymphoma (NHL) incidence include family characteristics, high fetal growth, older maternal age, low birth order, and male gender, according to a study published May 22 in the Journal of the National Cancer Institute.

Over the last 50 years, NHL incidence increased substantially, although the overall incidence started to stabilize in the 1990s, at least among adults. But incidence has continued to climb in children, adolescents, and young adults. Perinatal factors have been thought to increase NHL risk, but previous studies of those factors were limited due to small sample sizes, wide variability in adjustment for confounding, and possible selection bias such as socioeconomic circumstances.

In order to determine the cause of NHL incidence in children, adolescents, and young adults, Casey Crump, M.D., Ph.D., of the Department of Medicine at Stanford University and colleagues, conducted a national cohort study of more than 3.5 million people born in Sweden between 1973-2008 who were followed for NHL incidence through 2009. Information on perinatal and family characteristics and NHL diagnoses were attained through linkage of national birth and cancer registries, and Cox proportional hazard models were used to assess association of those characteristics with the risk of NHL.

The researchers found that genetics and in utero conditions contributed to the incidence of NHL in adolescents. The strongest link was a family history of NHL in either a sibling or parent. A high fetal growth rate, older maternal age, and low birth order also played a key role in incidence rates. Male gender was linked with NHL incidence in children younger than age 15, but not with later onset of NHL. "These findings suggest several heterogeneous mechanisms including possible growth factor pathways in utero, immunologic effects of delayed infectious exposures, as well as other unmeasured environmental and genetic factors," the authors write. "Further elucidation of these risk factors may facilitate the identification of high-risk individuals at young ages and potentially enable earlier detection and treatment."

In an accompanying editorial, William F. Anderson, M.D., M.P.H., and Benjamin Emmanuel, MPH, of the National Cancer Institute at the Division of Cancer Epidemiology and Genetics, write that this is a "well-performed national cohort study," but point out certain limitations, including: the unavailability of host and environmental risk factors such as radiation and environmental contaminants. They also point out the small number of case patients. However, they conclude that the study's, "large-scale and population-based design minimized selection bias and maximized generalizable conclusions for associations between NHL in early life and family history, high fetal growth weight, older maternal age, low birth order, and male sex."

###

Contact Info:

Article: Casey Crump. kccrump@stanford.edu

Editorial: William F. Anderson, wanderso@mail.nih.gov


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?


AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


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Monday, May 21, 2012

Donor aortic graft improves reconstruction after partial laryngectomy

Donor aortic graft improves reconstruction after partial laryngectomy [ Back to EurekAlert! ] Public release date: 21-May-2012
[ | E-mail | Share Share ]

Contact: Mike Morrison
mdmorrison@partners.org
617-724-6425
Massachusetts General Hospital

Novel grafts reduces need for permanent tracheotomy, maintain voice and swallowing function

Massachusetts General Hospital (MGH) surgeons have developed a new technique for reconstructing the larynx after surgery for advanced cancer. In the May Annals of Otology, Rhinology and Laryngology, they describe how this approach which uses cryopreserved aortas from deceased donors to replace removed larynx tissue allowed patients to avoid a permanent tracheotomy and maintain voice and swallowing function with no need for immunosuppressive medications. The pioneering surgery was a collaborative effort between Steven Zeitels, MD, director of the MGH Center for Laryngeal Surgery, and John Wain, MD, surgical director of the MGH Lung Transplantation Service.

"Without this new reconstructive technique, most of these patients would have required a total laryngectomy," says Zeitels, corresponding author of the report. "I don't believe anything like this has been achieved before especially for larynx cancer reconstruction in patients whose tumors recurred after radiotherapy."

Although small laryngeal tumors can be successfully removed through minimally invasive laser surgery or treated with radiation, advanced tumors require more invasive procedures to remove the affected area, especially when chemotherapy and radiation have failed as initial treatment. In these situations, problems with the healing of tissues previously exposed to radiation and the lack of reliable reconstructive techniques have meant that a majority of patients having partial laryngectomy still needed a permanent tracheotomy an opening through the neck and into the trachea resulting in substantial voice and swallowing dysfunction. Since the quality of life would probably be better with removal of the entire larynx, patients and their surgeons often chose a total laryngectomy.

To address the reconstructive limitations of partial laryngectomy, Zeitels and Wain developed an approach using the body's largest blood vessel, the aorta, to reconstruct the larynx. The MGH surgeons first used a previously frozen aortic graft for reconstruction after partial laryngectomy for recurrent cancer in 2009. Over the next two years, they performed the procedure on 15 patients, 8 of whom had previously received radiation therapy. All of these procedures were performed in one operation, combining both the tumor removal and reconstruction at the same time, and no immunosuppressive medications were needed.

Of that initial group of patients, all were able to have their postoperative tracheotomy tubes removed and resume breathing normally. All resumed speaking without the need for assistive devices, although their vocal quality depended on how much tissue had been removed, and all but one recovered and maintained swallowing function. Two patients had recurrence of their advanced tumors that required subsequent total laryngectomy. No stents were needed to keep patients' airways open, unlike in pilot trials using similar aortic grafts to reconstruct the trachea, which have had limited success.

"The shape of the aorta, which approximates that of the removed laryngeal tissue, and its ability to serve as a surface for healing within the airway are unique characteristics of these grafts that other forms of reconstruction do not provide," says Wain.

Zeitels adds, "The success of this procedure is remarkable, since the aortic tissue has held up extremely well against the stresses of a non-sterile environment, exposure to refluxing stomach fluids and the mechanical forces of swallowing and coughing. Given the success in this extremely challenging surgical scenario, it's likely that there will be many other uses for cryopreserved vascular grafts as supportive structures and tissue patches for surgery in other parts of the body."

###

Zeitels is the Eugene B. Casey Professor of Laryngeal Surgery, and Wain is an assistant professor of Surgery at Harvard Medical School. The study was supported, in part, by grants from the Voice Health Institute, the V Foundation and the Eugene B. Casey Foundation.

Massachusetts General Hospital, founded in 1811, is the original and largest teaching hospital of Harvard Medical School. The MGH conducts the largest hospital-based research program in the United States, with an annual research budget of more than $750 million and major research centers in AIDS, cardiovascular research, cancer, computational and integrative biology, cutaneous biology, human genetics, medical imaging, neurodegenerative disorders, regenerative medicine, reproductive biology, systems biology, transplantation biology and photomedicine.


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?


AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


Donor aortic graft improves reconstruction after partial laryngectomy [ Back to EurekAlert! ] Public release date: 21-May-2012
[ | E-mail | Share Share ]

Contact: Mike Morrison
mdmorrison@partners.org
617-724-6425
Massachusetts General Hospital

Novel grafts reduces need for permanent tracheotomy, maintain voice and swallowing function

Massachusetts General Hospital (MGH) surgeons have developed a new technique for reconstructing the larynx after surgery for advanced cancer. In the May Annals of Otology, Rhinology and Laryngology, they describe how this approach which uses cryopreserved aortas from deceased donors to replace removed larynx tissue allowed patients to avoid a permanent tracheotomy and maintain voice and swallowing function with no need for immunosuppressive medications. The pioneering surgery was a collaborative effort between Steven Zeitels, MD, director of the MGH Center for Laryngeal Surgery, and John Wain, MD, surgical director of the MGH Lung Transplantation Service.

"Without this new reconstructive technique, most of these patients would have required a total laryngectomy," says Zeitels, corresponding author of the report. "I don't believe anything like this has been achieved before especially for larynx cancer reconstruction in patients whose tumors recurred after radiotherapy."

Although small laryngeal tumors can be successfully removed through minimally invasive laser surgery or treated with radiation, advanced tumors require more invasive procedures to remove the affected area, especially when chemotherapy and radiation have failed as initial treatment. In these situations, problems with the healing of tissues previously exposed to radiation and the lack of reliable reconstructive techniques have meant that a majority of patients having partial laryngectomy still needed a permanent tracheotomy an opening through the neck and into the trachea resulting in substantial voice and swallowing dysfunction. Since the quality of life would probably be better with removal of the entire larynx, patients and their surgeons often chose a total laryngectomy.

To address the reconstructive limitations of partial laryngectomy, Zeitels and Wain developed an approach using the body's largest blood vessel, the aorta, to reconstruct the larynx. The MGH surgeons first used a previously frozen aortic graft for reconstruction after partial laryngectomy for recurrent cancer in 2009. Over the next two years, they performed the procedure on 15 patients, 8 of whom had previously received radiation therapy. All of these procedures were performed in one operation, combining both the tumor removal and reconstruction at the same time, and no immunosuppressive medications were needed.

Of that initial group of patients, all were able to have their postoperative tracheotomy tubes removed and resume breathing normally. All resumed speaking without the need for assistive devices, although their vocal quality depended on how much tissue had been removed, and all but one recovered and maintained swallowing function. Two patients had recurrence of their advanced tumors that required subsequent total laryngectomy. No stents were needed to keep patients' airways open, unlike in pilot trials using similar aortic grafts to reconstruct the trachea, which have had limited success.

"The shape of the aorta, which approximates that of the removed laryngeal tissue, and its ability to serve as a surface for healing within the airway are unique characteristics of these grafts that other forms of reconstruction do not provide," says Wain.

Zeitels adds, "The success of this procedure is remarkable, since the aortic tissue has held up extremely well against the stresses of a non-sterile environment, exposure to refluxing stomach fluids and the mechanical forces of swallowing and coughing. Given the success in this extremely challenging surgical scenario, it's likely that there will be many other uses for cryopreserved vascular grafts as supportive structures and tissue patches for surgery in other parts of the body."

###

Zeitels is the Eugene B. Casey Professor of Laryngeal Surgery, and Wain is an assistant professor of Surgery at Harvard Medical School. The study was supported, in part, by grants from the Voice Health Institute, the V Foundation and the Eugene B. Casey Foundation.

Massachusetts General Hospital, founded in 1811, is the original and largest teaching hospital of Harvard Medical School. The MGH conducts the largest hospital-based research program in the United States, with an annual research budget of more than $750 million and major research centers in AIDS, cardiovascular research, cancer, computational and integrative biology, cutaneous biology, human genetics, medical imaging, neurodegenerative disorders, regenerative medicine, reproductive biology, systems biology, transplantation biology and photomedicine.


[ Back to EurekAlert! ] [ | E-mail | Share Share ]

?


AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


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Growing Demand for Strategic Workforce Planning Leaders in ...

By the Conference Board, Special for US Daily Review.

As organizations continue to confront the long- and short-term impact of the Great Recession, businesses recognize that, in many cases, it is crucial to implement a strategic workforce plan, or a strategy to realign human capital needs to match the overall business strategy.? Because strategic workforce planning (SWP) is still a new methodology, there is no established profile of the successful SWP leader and no proven process for finding such a person, according to a recent Executive Action Report from The Conference Board.

?The shortage of experienced SWP leaders is an issue for businesses looking to deploy a three-to-five year SWP process,? said?Mary B. Young, D.B.A., Principal Researcher, Human Capital, The Conference Board. ?Interestingly, our research shows that while many SWP leaders have HR experience, that?s not always the case. In fact, effective SWP leaders are likely to have diverse work experiences within and outside of HR.?

There are 10 skills and competencies that SWP leaders must have to be effective.?Business knowledge, analytical expertise and change leadership?are essential requirements that prospective SWP leaders must have.??Collaboration, stature and credibility, intellectual capacity, communications skills, scenario-planning skills, diverse experience?and?belief in SWP?are seven important factors that individual SWP leaders must possess or must develop to be effective.

Surprisingly, many SWP leaders have spent at least some of their careers outside the human resources (HR) function, working in finance, corporate planning, sales, marketing or as a line manager. That background helps them demonstrate the?businessvalue of SWP, rather than presenting it as an HR exercise. SWP translates business strategy into HR strategy to ensure that workforce decisions and investments are aligned with business priorities.

And as ?big data? ? or volumes of data ? are becoming increasingly important in many areas of the business, there?s a growing demand for expertise in analyzing and using data for competitive advantage. Companies seeking an SWP leader may not only find few ready candidates; they may have to compete with other functions that are also hunting for analytical talent.

For complete details:
http://www.conference-board.org/publications/publicationdetail.cfm?publicationid=2134

Report: ??Where do SWP Leaders Come From
(Executive Action Report)
By?Mary Young

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Sri Lanka president orders release of jailed rival

COLOMBO (Reuters) - Sri Lanka's President Mahinda Rajapaksa has ordered the early release from jail of his highest-profile political rival Sarath Fonseka, the president's spokesman said on Sunday, in an apparent bid to quell international criticism of the government's human rights record.

The authorisation for Fonseka's release will be sent to the justice ministry on Monday, spokesman Bandula Jayasekara said. The former general is expected to be free soon afterwards, but will not be able to leave the country.

"(The) president signed the papers on Friday evening enabling the release of Sarath Fonseka," Jayasekara said.

The United States calls former army general Fonseka, who was detained in February 2010 after challenging Rajapaksa for the presidency, a political prisoner, and has repeatedly said he should be freed.

Many Sri Lankans regard Fonseka as a hero for helping to end the 25-year civil war against the Tamil Tiger rebels, and his case has gained prominence as international scrutiny of the Rajapaksa administration's human rights record has intensified.

At a meeting in Washington on Friday, Secretary of State Hillary Clinton called on Sri Lanka's foreign minister to address human rights issues.

In March, the U.S. sponsored a United Nations resolution calling on the Colombo to investigate abuses alleged to have taken place in the final months of the war, a move which strained ties between the countries.

Rajapaksa has until now defied the U.N. and U.S. criticism of his handling of the war's aftermath. Local analysts says Fonseka's release is partly aimed at distracting from local complaints about poor economic management.

Last week, news of his impending liberation was welcomed by investors who hoped it would improve Sri Lanka's international image, and prompt more foreign inflows.

His health has deteriorated in prison, and for the last few weeks he has been under guard in a hospital where he is being treated for respiratory problems stemming from war wounds.

POPULAR LEADER

Economic woes pushing up the cost of living have dented the government's popularity ahead of local elections this year, and Rajapaksa's decision could increase his party's chances by dividing the bickering opposition.

Fonseka leads the Democratic National Alliance, which has seven seats in a 225-member legislature, and some lawmakers from other opposition parties have said they are ready to back him, citing his popularity and strident criticism of Rajapaksa.

He trailed Rajapaksa by 17 points in the last presidential election. With the next one not due until 2016, he is not seen as an immediate political threat, although he remains a popular leader. His poor health has increased pressure on Rajapaksa to set him free.

In Washington on Friday, Clinton told foreign minister G.L. Peiris that Sri Lanka should demilitarise the former Tiger strongholds in the north of the country. Rajapaksa responded by saying he would not be dictated to on matters of national security.

Fonseka and the president's brother, Defense Secretary Gotabaya Rajapaksa, led the army to victory in the final stages of the war, but they fell out in peacetime. The general complained he was sidelined by the president, who grew concerned Fonseka was plotting a coup.

Fonseka is serving two separate jail terms, one for misappropriation of funds and another for giving an interview in 2009 in which he said he was informed that Gotabaya Rajapaksa ordered troops to kill surrendering rebel leaders.

Rights groups say both Fonseka and the president are implicated in shooting Tamil fighters as they sought to surrender. In recent months, rights workers and journalists have been targeted by a government media campaign against "traitors" it says helped the defeated guerrillas.

(Writing by Frank Jack Daniel; Editing by Daniel Magnowski)

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Sunday, May 20, 2012

World News - Obama, NATO leaders chart path out of Afghanistan

By NBC News and news services

Updated 6:22 p.m. ET: CHICAGO -- President Barack Obama on Sunday pressed world leaders to help implement a strategy for post-2014 Afghanistan after U.S. troops leave, a transition that Afghan President Hamid Karzai said will mark the day that his war-torn country is "no longer a burden" on the rest of the?world.

Obama and Karzai met on the sidelines of the NATO summit on Sunday to discuss Afghanistan's post-conflict future. After the meeting, Obama told reporters that the two-day summit would focus on Afghanistan's move to peace and stability after a decade of war.


"We still have a lot of work to do and there will be great challenges ahead," Obama said. "The loss of life continues in Afghanistan and there will be hard days ahead."

Standing next to Obama, Karzai reaffirmed his commitment to the transition timetable?process, which he said will lead to a time when Afghanistan "is no longer a burden on the shoulder of our friends in the international community, on the shoulders of the United States and other allies."

Karzai also thanked Americans for the help that their "taxpayer money" has done in?Afghanistan.

Pablo Martinez Monsivais / AP

President Barack Obama, right, shakes hands with with Afghan President Hamid Karzai during their meeting at the NATO summit in Chicago on Sunday.

"Afghanistan is fully aware of the task ahead and of what Afghanistan needs to do to reach the objectives that we all have of a stable, peaceful and self-reliant Afghanistan," he said.

President Barack Obama welcomes foreign leaders to the NATO summit in Chicago. NBC's Kristen Welker reports.

Obama later opened the summit by telling world leaders: "For over 65 years our alliance has been the bedrock of our common security, our freedom and our prosperty, and although times have changed the reasons for our alliance has not."

Obama urged NATO leaders to ratify a "broad consensus" for gradually turning over security to Afghan forces and pulling out most of the 130,000 NATO troops by the end of 2014.

Earlier, a top NATO official?insisted?that the Afghanistan fighting coalition will remain whole despite France's plans to yank combat troops out early.

"There will be no rush for the exits," NATO Secretary General Anders Fogh Rasmussen said. "We will stay committed and see it through to a successful end. Our goal, our strategy, our timetable remain unchanged."

NATO leaders gathered in Chicago to chart a path out of Afghanistan as war-weary Western nations seek to fend off dissent in their alliance and ensure Afghanistan can hold a still-potent Taliban at bay when foreign troops withdraw.

Obama was hosting the two-day summit in his hometown, a day after leaders of major industrialized nations tackled Europe's debt crisis, backing keeping Greece in the euro zone and vowing to take steps necessary to revitalize the world economy.

Public opinion in Europe and the United States is solidly against the war, with a majority of Americans now saying it is unwinnable or not worth continuing.

Newly elected French President Francois Hollande has said he will withdraw all French combat troops from Afghanistan by year's end ? a full two years before the timeline agreed to by nations in the U.S.-led NATO coalition.

"President Hollande has stated that France would be prepared to support Afghanistan in a different way," Rasmussen said.

But signaling tensions over the issue, German Chancellor Angela Merkel told reporters: "We went into Afghanistan together, we want to leave Afghanistan together."

Hollande repeated a pledge during his inaugural visit to Washington last week to pull "combat troops" from Afghanistan this year. He has said an extremely limited number of soldiers would remain to train Afghan forces and bring back equipment beyond 2012.

"This decision is an act of sovereignty and must be done in good coordination with our allies and partners," said Hollande, who was?to discuss his exit plans with Karzai.

A last-minute addition to the list of leaders at the NATO meeting was President Asif Ali Zardari of Pakistan, whose western tribal areas provide shelter to militants attacking Karzai's government and NATO forces. He pressed the United States to help find a "permanent solution'' to U.S. drone strikes that have fueled tensions between the two uneasy allies.

"The president said that Pakistan wanted to find a permanent solution to the drone issue as it not only violated our sovereignty but also inflamed public sentiments,'' Zardari spokesman Farhatullah Babar said in a statement after the Pakistani leader met with U.S. Secretary of State Hillary Clinton on the sidelines of the summit.

The statement did not specify what such a solution might entail.

Gen. John Allen, the U.S. commander in Afghanistan, told Reuters he was confident a deal would eventually be struck but "whether it's in days or weeks, I don't know."

Zardari also called for the United States to do more to make amends for the deaths of 24 Pakistani soldiers killed in November by U.S. aircraft along the border with Afghanistan.

Pakistan has demanded a high-level apology for that incident, which the White House has resisted so far.

Fiscal demands, including plans for major cuts to defense spending in Europe and the United States, were sure to color the talks in Chicago, as they did those between G-8 leaders.

The overarching message from that G-8 summit reflected Obama's own concerns that euro-zone contagion, which threatens the future of Europe's 17-country single currency bloc, could hurt a fragile U.S. recovery and his re-election chances.

Information from The Associated Press and Reuters?is included in?this report.

More NATO coverage:

US veterans return war medals in NATO protest
Great-grandmother: Ready to 'lose my life' protesting

Storify: Scenes from NATO summit protesters

Video: Police say?Chicago protesters planned bombings

?

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